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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1249ca20d30f758b5e2cc0a63c371137cbbe3037e10566d070282175da8f94e8' 
  AND token = 'RXFOfDDVdVttaqkcn1fZ6c6FdiE88SmeOCOeF+/+KpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}