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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3f7b5ee00bd040821723a2825ece0b8c0ada1d8a23298eaa244485b70d43d71' 
  AND token = 'KzAbzp3+b0mhMrx/YNq+qq6VvQXUlh/h4kh2s/LXe4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}