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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e786cbd49a53b7cf738b3c8450c6ec5953f3ee75d7cc4e7ad3b635af29fe0dfd' 
  AND token = 'Ky/DtaJbENq/O3fXtWEgL4MtjclPDDXEUTPxhmmf0Dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}