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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0521cdd651b97cd9629717a9f2277d6d733c3609ed6230d8947ee762fbf5abb6' 
  AND token = 'XIs7P3/xp9VrcleoJ5o1xdWJHATFe9yRcafQd9XqOB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}