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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a8fe6efb68ac1d5c99edda60f402a109fa63d188adbc32a2a61149753d97c89' 
  AND token = 'k3XBwrVsTFXb2klzJ6zSITJjmCxWAok5GzRLa6zWfc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}