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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '647ebe8ae2a0da34f1bfd4a6c81e0a3e9a3d297ce74f064f1debe54b3f44bef0' 
  AND token = '7Hl+7oY2O2Qy2KU7IIdbB/BDs1xrFEHMy0z56zHqLzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}