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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '798f96d24e4b85c2ab37bc7c375c8f583ff7fd64d13243fca710a80d4ae659ad' 
  AND token = '7xk4w+UK9COSEw63bqlJKdDsER5oztDv0bOA19agF/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}