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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4e8763d030072ccb7d779a60ffd5540b19935f5b1a357aee9a07d543203eddd' 
  AND token = 'nRQk+CSbW0atTOJZnacWZ57amhrhWR2Xb2ydww26mPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}