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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4ef6c6cfaebebb65ba4ff2678c625a0e6f3243491022c7c285d823b04bbe4a2' 
  AND token = 'j1JnBGNQyiUeTtQtmT5PA6CyEEyZwT+wpKz8q3NzbkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}