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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d8acc96056d806e38533e5d3bcb9da8859e2ab6828b3edac67fbe436ea0e94d' 
  AND token = '/dg4ZfAXV/xz3JxnYdgkb2qoMdqICEFFZPMKrwGz8nY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}