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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bcf80d4033e017e5d36479cbf59e9fa0d642dc9eab536fdf9c655126c2cfdac2' 
  AND token = 'OwH4BcEHdBzGo9oFyoOEPVJ3SmZer2PqPrR0Z2lTSTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}