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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '163347a561ca4e11938ed29768dd20d196cd20d8b53b882dd2a19dc41dc401a0' 
  AND token = 'nUTJotfLniGGtptd40pXLU1fp1BEseklezzDbFKqYNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}