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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f02d7de25b24f3219bf07cd1a9d34897df3d91e7e52abf6188e94e83aefbb53' 
  AND token = 'O5UKIdiTYDfBm239l06vgpxOKG3++3fDkzzRfXyJ7NY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}