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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7db4b413f862982a5f1f3d9db172cc01b2206e566bb7c52066189f052729dd2' 
  AND token = '3B5Bea1pQPzBY4PXX9NkUHszcY5TphnRLOKVTxBKL4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}