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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12b998dbae3e9d275d1db19416c24fffa8bc447da7f36f6300f3e005fe2f4038' 
  AND token = 'sH7/yWB0wkeuhqubv3Jf0f6WSob86GC9gIJ/q2TFHB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}