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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a456023fe7729ea2e686b59c6571567c85357e4b49a3be009b6fbaebbfedc25e' 
  AND token = 'cnDPOt8IEIig6QO1hzGwPVyBQ9Qj/yEwwTXZ+LeB8PM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}