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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ecb7a91795992e0fce17ec3f2406b724b7e2616b64649aec2933c29dbdfa4f1' 
  AND token = 'tIkhQiUIQfd//ECc6x59+wLFMnSE4clsinjOHV/4C2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}