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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26a98af5a6798ce88ea196f5dda960466b4aa4c01f991015391e8d7a26e91a6d' 
  AND token = 'q3Cg23x5OsNUBBcvqA3TTGd8zrRUXvSaJVGQRXcJ5ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}