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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a17435a052cd71b442c18bee6301f1cbbed018f2c9f7c257e12198eb21dd5275' 
  AND token = 'AS5gI1h4L4+qE+KZ6PWxD8tk/zq1wCQSJnQh+2WPw1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}