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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5019f95a82b0b62625c9985de49d45bec0bd7ddf7846ecb7f880b8d38e48c354' 
  AND token = 'nsGMC4BGVYS0shPoSCTdlUn+7saeQ0HWQeTqvNSUbUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}