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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba1647d6ac19d92f590503b4aad7d4f789c5f8f4b0681e7424bcc565d4132e72' 
  AND token = 'JaeLs8I922gN3JNUVxB2EUHB6wW4bH3Yxkrgj1qQ9bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}