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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '229227ad08c58306b5f8e3d7d7e1451573171332e1d013bea61ef801c7b53cc4' 
  AND token = 'YlborspZF+PG+ceIgoSa0ygXO5WFrDXvG8wrIhCeN6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}