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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec351d14860fe4e9cc0285a0c0c9441b23e1d5bb2833f7a7a59ee770586d850a' 
  AND token = 'D6NkNwyftoEDmrgJDhA4dCNzO1zEN2UHGNPSrVy2Mzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}