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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa4f3e1a8cda965e1a4d7ba5055dc3007044b1fbd75e032a0f553ad1877f3dfd' 
  AND token = 'z2IZ4ojU1t9djH1LfZRmvNsnn4H40PfHRsrjFN1PlBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}