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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cb6013007a5e4c00db7c0e82438e992a3c1b029b6a575d12768aba11670be0d' 
  AND token = 'HwrRzZJXu63PT9CuvUoweBrrPY5yfsshr/xMk5tGjVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}