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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7415dc0f3fc5ebacabec7c332a30378a633b636bfd70d71039d85b3212551ec7' 
  AND token = 'uxO1yC5tI0WCVaPqXIJ5v9rOb92teJ7A5aQ4+US+UMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}