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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b3affbe20010cddc3a4f8a8fc0306e5c2f2a298216d914b600e1b292941f521' 
  AND token = 'wPNFt/Y8rrh/xKmr9Bnn5V6sXN5ambA4b0riWu9zVnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}