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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73c1651a62b25b63560a735625c7e9b83aef04edf6f64ea10129db4c04645317' 
  AND token = 'mAsUkQvfvmbA37o2X+4QM8veqhxDChOeQx1bc8vVWJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}