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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5740b54959f8ce6e8e1799bb543eb5bd4badaa10eef58f897da8715379f900ef' 
  AND token = 'dZ/NkT7Zq9a3yPdDrglDVhXbORNfdsQEHsaQE8tG6NY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}