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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb77e11e2982c52c5d330e60a29d18ec5e728a5f56d3ca9149251a34b8f58da5' 
  AND token = 'tnomFaH9CBesBrMCgz35QKOeuElX99TeZ8QVh4C73zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}