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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5b69235730f6064d224bed5c8267569b5b618be8c38541f782bf11c10030352' 
  AND token = 'vJiLCeyK0ckRx5AU0m+/2LQe9LMI4TJ/EL46JXuNm50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}