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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ecf3b1ecf0a48031a78bc44c7f59c769611b5c4e15810388d971afa45f5b8f4' 
  AND token = '7TnxpK4KJyjxO+DE0+1+C/47J7f9BcZ9ox/GpamJ0y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}