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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b452c43b07f3e196178b7e4017970ba25e602243ced25e8c4cbd06cfd7ca6286' 
  AND token = '4BKGKjXEP418PBj9lHgaElqjCUaAaBug3BwMaaYmk9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}