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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c48505d58f2ef40c1ffa7896ac8249acf46f18d5de83fb0db0b09f79f0cc051' 
  AND token = '701DUgVlwxWsuiUd7U4iMlS+wln6ihVDRlDKwFMWRIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}