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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ad2dec3ca34640cbe923b1716af97f80734c06bfa1ee33eb1d2229cd78c4e8' 
  AND token = 'hGeYeRIbXL+e+AyuSnAB3MWRNwQ259Ne026s+6t1qgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}