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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee72813fd26fc16a033806a5a3f9d96115f165a93d9b0d2836d7058f4f5a5788' 
  AND token = 'LqHWHupAHAoeI1ms+I5pVPoPU3sbf6f5rVkY1SlcH3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}