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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1a117d76c4474f3c3744da4427980081c67a26b72717c8793644f1089fa2ff1' 
  AND token = '3xqMJQka/JgcCi+1MmPGu/CO6ClqNX7x8ZgT11S3GTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}