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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e156da0c07fed110130f9ca831b4b884ffd8336ad7074012e4507511141e5f84' 
  AND token = '6+Wm6Mn2T39NCYwV8aSu1qJlmmFEeb7c0wpmx9m2BnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}