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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eac7b4f22a4044c118fc5a2de4e1a987a4097346c265c3af9a38a4d90715e05' 
  AND token = 'lwxqnImakRRvFK7RSUDZDZiH4jSEKRSgm1+2S9dmhH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}