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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8610ef1e6c5434133c8c2819e2afe68d1bad78d80b7d225b86335e669b0218f' 
  AND token = 'OeyxfqsSno8R0FxrxWTklA0Uzixh3sj80PmB5aPWva0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}