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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71ac48b2fbe64096d8b2b8fccf7ec5f233d40ed1921e179415004f05b5c5a594' 
  AND token = 'SI3DrmTRXCu2p+DJZaD9hGRRNtv5/FiEpAK10UpwL3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}