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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6b4a74d2a8fbe72ad2256a61d09353b4188ac84ce95167c37756c79a8d4dfbb' 
  AND token = '2DReHyxuL448EFIC1rsmveQq7es6qIlFFh34LhXRXjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}