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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a9303ed3c0075204729aa432454c8b4200e31ecbde455c2ccc1f1a294180ed6' 
  AND token = 'Jp2P5fjfnd6z0DGgzj0ufHiCT1VXAz0JZ/FXIJf8lbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}