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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a0fb02f381c54e5e1db41f25d3e196e0d36ebc40a2e03cd67ef7c83913d3605' 
  AND token = 'ltc4cn3DFSXl1U0K3OowxYjU70fqztYeU+eQIu5vhb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}