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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '208c1f9dcfc0aacd35c7d6664d2e3379fb837adb2de10e5733fc9794c05d88dc' 
  AND token = 'g1YQLLY7jBVkrZ1s2/xYkHQ924+UIp+gSf+xgR/dUXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}