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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64774825f64bd4f7cdad5e72cf0c77f2c903b60904ad15964c1451164856665c' 
  AND token = 'jz8ppkc6kWDqdXMx3+HCrf9W4++doDt6izJGnKZ9X9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}