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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fe600396325d93ac00a5e693a9daf2749cb7473a9cd7dfa21324ade37a33853' 
  AND token = '1H/fR63Qgzd4unCebAD+M4PSlIRHqgoLWXUxIgwutgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}