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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97be66d2cd30cac8d69d924d67541d5500b52dc6f10b589b95659d0a109b5027' 
  AND token = 'Lsp0XNmrqxgd3Qdnt17AkAhNlHMYALt6MWMgUmXDeiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}