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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed0e64168ceaaed2288f276a0943c4361f4978735c14549ad2b3cc6468f7b889' 
  AND token = 'F5uQrOR2F3EiaUla31NXGa4lFT/HnshPifKLQBx1X/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}