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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f38e151dcc665c966f04bde232feea2cbf4edaf8d697a9e39f5374d692846d1c' 
  AND token = 'skJEj2wWxZ+Np4bCAmSu8PBOm9HN35mcOHB0ySY2fQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}